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Avicenna Journal of Neuro Psycho Phyisology، جلد ۲، شماره ۱، صفحات ۰-۰
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| عنوان فارسی |
In Vivo Antinociceptive Effects of Persian Shallot (Allium hirtifolium) in Male Rat |
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| چکیده فارسی مقاله |
Conclusions It looks that A. hirtifolium has antinociceptive effects that might be due to flavonoids and saponins in plant the analgesic effect of which was demonstrated previously. Results Allium hirtifolium extract at (200 mg/kg dosage), alone and in combination with aspirin, had shown antinociceptive effect in writhing, tail-flick, and formalin tests (P < 0.01). Allium hirtifolium extract (at 100 mg/kg dosage) had just shown analgesic effects on tail-flick and formalin (chronic phase) tests. Objectives In this investigation, analgesic effects of hydroalcoholic leaf extract of Allium hirtifolium were studied in male rats. Materials and Methods A total of 48 adult male rats were divided eight groups: control, intraperitoneal 50, 100, and 200 mg/kg of extract, 200 mg/kg of A. hirtifolium extract plus aspirin, aspirin (1 mg/kg), morphine (1 mg/kg), and 200 mg/kg of A. hirtifolium extract plus naloxone (1 mg/kg). The analgesic effects of A. hirtifolium were assessed with writhing, tail-flick, and formalin tests. The data were compared with control by one-way ANOVA and Tukey post hoc test. Background The tendency toward using herbal plants instead of synthetic drugs is increasing in recent years because of their lower adverse effects and high varieties of efficient components. |
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| کلیدواژه‌های فارسی مقاله |
Allium hirtifolium،Formaldehyde،Saponins،Flavonoids |
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| عنوان انگلیسی |
In Vivo Antinociceptive Effects of Persian Shallot (Allium hirtifolium) in Male Rat |
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| چکیده انگلیسی مقاله |
Conclusions It looks that A. hirtifolium has antinociceptive effects that might be due to flavonoids and saponins in plant the analgesic effect of which was demonstrated previously. Results Allium hirtifolium extract at (200 mg/kg dosage), alone and in combination with aspirin, had shown antinociceptive effect in writhing, tail-flick, and formalin tests (P < 0.01). Allium hirtifolium extract (at 100 mg/kg dosage) had just shown analgesic effects on tail-flick and formalin (chronic phase) tests. Objectives In this investigation, analgesic effects of hydroalcoholic leaf extract of Allium hirtifolium were studied in male rats. Materials and Methods A total of 48 adult male rats were divided eight groups: control, intraperitoneal 50, 100, and 200 mg/kg of extract, 200 mg/kg of A. hirtifolium extract plus aspirin, aspirin (1 mg/kg), morphine (1 mg/kg), and 200 mg/kg of A. hirtifolium extract plus naloxone (1 mg/kg). The analgesic effects of A. hirtifolium were assessed with writhing, tail-flick, and formalin tests. The data were compared with control by one-way ANOVA and Tukey post hoc test. Background The tendency toward using herbal plants instead of synthetic drugs is increasing in recent years because of their lower adverse effects and high varieties of efficient components. |
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| کلیدواژه‌های انگلیسی مقاله |
Allium hirtifolium,Formaldehyde,Saponins,Flavonoids |
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| نویسندگان مقاله |
سعید محمدی | saeed mohammadi
biology department, faculty of basic sciences, science and research branch, islamic azad university, tehran, ir iran
سازمان اصلی تایید شده: دانشگاه آزاد اسلامی علوم و تحقیقات (Islamic azad university science and research branch)
محمد زارعی | mohammad zarei
neurophysiology research center, hamadan university of medical sciences, hamadan, ir iran; physiology department, medicine faculty, hamadan university of medical sciences, hamadan, ir iran; neurophysiology research center, hamadan university of medical sciences, p. o. box 6517838736, hamadan, ir iran. tel 98-8138380462, fax 98-8138380464
سازمان اصلی تایید شده: دانشگاه علوم پزشکی همدان (Hamadan university of medical sciences)
مینو محمودی | minoo mahmoodi
biology department, faculty of basic sciences, hamadan branch, islamic azad university, hamadan, ir iran
سازمان اصلی تایید شده: دانشگاه آزاد اسلامی علوم و تحقیقات (Islamic azad university science and research branch)
محمد مهدی زارعی | mohammad mahdi zarei
veterinary medicine faculty, karaj branch, islamic azad university, karaj, ir iran
سازمان اصلی تایید شده: دانشگاه آزاد اسلامی علوم و تحقیقات (Islamic azad university science and research branch)
مهتاب عسگری نعمتیان | mahtab asgari nematian
biology department, hamadan branch, payam-noor university, hamadan, ir iran
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| نشانی اینترنتی |
http://www.avicennajnpp.com/index.php?page=article&article_id=27149 |
| فایل مقاله |
فایلی برای مقاله ذخیره نشده است |
| کد مقاله (doi) |
10.17795/ajnpp-27149 |
| زبان مقاله منتشر شده |
fa |
| موضوعات مقاله منتشر شده |
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| نوع مقاله منتشر شده |
research-article |
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