Avicenna Journal of Clinical Microbiology and Infection، جلد ۱، شماره ۱، صفحات ۰-۰

عنوان فارسی The Prevalence of Cryptosporidium Infection Among Renal Transplanted Patients in Hamadan City, West of Iran
چکیده فارسی مقاله Background Opportunistic infections have become much more considerable in the last decades, especially in immunocompromised patients and due to the medical interventions. Cryptosporidium is a pathogenic protozoan parasite causing diarrhea in children and some times acts as a life threatening opportunistic pathogen in the immunocompromised adults. Objectives This study aimed to investigate the presence of Cryptosporidium infection among patients undergone renal transplantation, who are at risk for this infection. Patients and Methods This was a cross-sectional study and the sample collection consisted of 180 renal transplanted patients referred to Shaheed-Beheshti Hospital, Hamadan city, Iran. The stool specimens were concentrated using formalin-ether technique and then the fecal smears were prepared from the sediments. Afterwards, the slides were stained using the Ziehl-Neelsen staining method and then examined for the presence of Cryptosporidium oocysts. Results One out of 180 fecal samples was positive for Cryptosporidium infection. The infected patient was a 51-year-old woman who had a renal transplantation six years earlier, with continuous use of CellCept® (mycophenolate mofetil) and prednisolone. The patient had been referred to the hospital with gastrointestinal symptoms. Conclusions Based on the results of this study the prevalence of cryptosporidiosis was very low in renal transplanted patients in Hamadan city, Iran. It could be concluded that cryptosporidiosis is not a life threatening risk in this region and it probably showed well post-transplantation hygienic status of the patients and/or low oocysts load in the area.
کلیدواژه‌های فارسی مقاله Cryptosporidium،Immunocompromised Host،Transplants،Iran

عنوان انگلیسی The Prevalence of Cryptosporidium Infection Among Renal Transplanted Patients in Hamadan City, West of Iran
چکیده انگلیسی مقاله Background Opportunistic infections have become much more considerable in the last decades, especially in immunocompromised patients and due to the medical interventions. Cryptosporidium is a pathogenic protozoan parasite causing diarrhea in children and some times acts as a life threatening opportunistic pathogen in the immunocompromised adults. Objectives This study aimed to investigate the presence of Cryptosporidium infection among patients undergone renal transplantation, who are at risk for this infection. Patients and Methods This was a cross-sectional study and the sample collection consisted of 180 renal transplanted patients referred to Shaheed-Beheshti Hospital, Hamadan city, Iran. The stool specimens were concentrated using formalin-ether technique and then the fecal smears were prepared from the sediments. Afterwards, the slides were stained using the Ziehl-Neelsen staining method and then examined for the presence of Cryptosporidium oocysts. Results One out of 180 fecal samples was positive for Cryptosporidium infection. The infected patient was a 51-year-old woman who had a renal transplantation six years earlier, with continuous use of CellCept® (mycophenolate mofetil) and prednisolone. The patient had been referred to the hospital with gastrointestinal symptoms. Conclusions Based on the results of this study the prevalence of cryptosporidiosis was very low in renal transplanted patients in Hamadan city, Iran. It could be concluded that cryptosporidiosis is not a life threatening risk in this region and it probably showed well post-transplantation hygienic status of the patients and/or low oocysts load in the area.
کلیدواژه‌های انگلیسی مقاله Cryptosporidium,Immunocompromised Host,Transplants,Iran

نویسندگان مقاله رسول جعفری | rasool jafari
department of parasitology and mycology, school of medicine, isfahan university of medical sciences, isfahan, ir iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی اصفهان (Isfahan university of medical sciences)

زهرا غریبی | zahra gharibi
department of parasitology, school of medicine, hamadan university of medical sciences, hamadan, ir iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی همدان (Hamadan university of medical sciences)

محمد فلاح | mohammad fallah
department of parasitology, school of medicine, hamadan university of medical sciences, hamadan, ir iran; deptartment of parasitology, school of medicine, hamadan university of medical sciences, hamadan, ir iran. tel 98-9181113650, fax 98-8112520203

سازمان اصلی تایید شده: دانشگاه علوم پزشکی همدان (Hamadan university of medical sciences)


نشانی اینترنتی http://www.ajcmicrob.com/index.php?page=article&article_id=19570
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کد مقاله (doi) 10.17795/ajcmi-19570
زبان مقاله منتشر شده fa
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نوع مقاله منتشر شده research-article
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