Background: Ankyloblepharon filiforme adnatum is a rare congenital anomaly characterized by partial or complete adhesion of upper and lower eyelids. This condition is usually observed as an isolated finding; however, it is often associated with other anomalies or a well-defined syndrome. The etiology of this defect has not been identified yet.
Case Presentation: Herein, we reported the case of a four-day-old male neonate who was unable to open his right eye at birth, which was due to adherent upper and lower eyelids as revealed in the physical examination. Family history of the patient was unremarkable. At sterile condition and under anesthesia, the adhesion of the eyelid was cut using a westcott scissor after holding the band of skin with forceps. Systemic and ocular examination did not reveal any abnormalities.
Conclusion: Ankyloblepharon filiforme adnatum is a congenital anomaly that can lead to amblyopia. The accompaniment of this defect with other congenital abnormalities may account for mortality. The early treatment of this anomaly through a simple surgery prevents amblyopia.