Avicenna Journal of Dental Research، جلد ۳، شماره ۲، صفحات ۹-۱۲
عنوان فارسی Biochemical Evaluation of the Effect of Green Tea on Nitric Oxide Radical in Patients with Chronic Periodontitis
چکیده فارسی مقاله Statement of the problem Periodontal disease is a periodontal tissue inflammation caused by gram-negative and other bacteria. The release of various cytokins and mediators, including nitric oxide, in the inflammation area usually has determental effects on the periodontium, potentiating the inflammatory process. In order to prevent this side effect, investigatiors have used anti-oxidants such as green tea or nitric oxide synthase inhibitors as a remedy. Purpose In this study the effect of green tea on salivary nitric oxide radical was investigated in patients with chronic periodontitis Materials and methods Two groups of patients (n=10), sufferring from chronic periodontitis as control and case groups, were evaluated. The case group used green tea for a period of four weeks. The control group received no intervention. At the end of this period the salivary total nitrite concentration as an indicator of nitric oxide was measured by ELISA technique based on Griess reaction. The results were compared statistically by paired-t-test at P< 0.05. Results Green tea reduced the salivary concentrations of nitric oxide significantly (P=0.000) in the case group in comparison with the control group which recieved no treatment. Conclusion The results indicated that green tea may be considered a useful herb for treatment of chronic periodontitis.
کلیدواژه‌های فارسی مقاله Green tea، Nitric oxide، Periodontitis
عنوان انگلیسی Biochemical Evaluation of the Effect of Green Tea on Nitric Oxide Radical in Patients with Chronic Periodontitis
چکیده انگلیسی مقاله Statement of the problem Periodontal disease is a periodontal tissue inflammation caused by gram-negative and other bacteria. The release of various cytokins and mediators, including nitric oxide, in the inflammation area usually has determental effects on the periodontium, potentiating the inflammatory process. In order to prevent this side effect, investigatiors have used anti-oxidants such as green tea or nitric oxide synthase inhibitors as a remedy. Purpose In this study the effect of green tea on salivary nitric oxide radical was investigated in patients with chronic periodontitis Materials and methods Two groups of patients (n=10), sufferring from chronic periodontitis as control and case groups, were evaluated. The case group used green tea for a period of four weeks. The control group received no intervention. At the end of this period the salivary total nitrite concentration as an indicator of nitric oxide was measured by ELISA technique based on Griess reaction. The results were compared statistically by paired-t-test at P< 0.05. Results Green tea reduced the salivary concentrations of nitric oxide significantly (P=0.000) in the case group in comparison with the control group which recieved no treatment. Conclusion The results indicated that green tea may be considered a useful herb for treatment of chronic periodontitis.
کلیدواژه‌های انگلیسی مقاله Green tea, Nitric oxide, Periodontitis
نویسندگان مقاله m جهانگیرنژاد | m jahangirnezhad
associate p rofessor. department of p eriodontology, f aculty of dent istry , ahwaz jundishapour u niversity


سید محمد غفاری | s m ghaffari
associate professor, department of biochemistry, faculty of medicine, ahwaz jundishapour university of medical sciences, ahwaz, iran, iran


l خسروی فارسانی | l khosravi farsani
doctor of dental medicine, ahwaz jundishapour university of medical sciences, iran


f جلالی | f jalali
doctor of dental medicine, ahwaz jundishapour university of medical sciences, iran
نشانی اینترنتی http://www.avicennajdr.com/index.php?page=article&article_id=18484
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