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Avicenna Journal of Medical Biochemistry، جلد ۳، شماره ۱، صفحات ۰-۰
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| عنوان فارسی |
Association of Adipokine Resistin With Homeostasis Model Assessment of Insulin Resistance in Type II Diabetes |
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| چکیده فارسی مقاله |
Conclusions Based on these data, we can argue that circulating glucose concentration is not directly affected by serum resistin in T2DM. It seems that resistin affects glucose indirectly, through insulin resistance. Results We found that serum resistin had a positive significant correlation with insulin resistance (P = 0.000, r = 0.64). No significant correlation was found between serum resistin and fasting glucose concentration in the studied patients (P = 0.21, r = 0.23). Background Resistin is a recently discovered signal molecule that has been linked to obesity, type II diabetes mellitus (T2DM) and metabolic syndrome. Objectives This study aimed to assess whether serum resistin is associated with insulin resistance and glucose concentration in males with T2DM. Patients and Methods Thirty two adult non-trained males with type II diabetes, 34-48 years old and 88-110 kg of body weight, participated in this study by accessible sampling. Fasting blood samples were collected from all participants in order to measure serum resistin, insulin and glucose concentration. Homeostasis Model Assessment of Insulin Resistance (HOMA-IR) was calculated using fasting insulin and glucose. Relations between variables were determined by Pearson correlations. |
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| کلیدواژه‌های فارسی مقاله |
Resistin،Body Weight،Insulin Resistance،Obesity |
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| عنوان انگلیسی |
Association of Adipokine Resistin With Homeostasis Model Assessment of Insulin Resistance in Type II Diabetes |
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| چکیده انگلیسی مقاله |
Conclusions Based on these data, we can argue that circulating glucose concentration is not directly affected by serum resistin in T2DM. It seems that resistin affects glucose indirectly, through insulin resistance. Results We found that serum resistin had a positive significant correlation with insulin resistance (P = 0.000, r = 0.64). No significant correlation was found between serum resistin and fasting glucose concentration in the studied patients (P = 0.21, r = 0.23). Background Resistin is a recently discovered signal molecule that has been linked to obesity, type II diabetes mellitus (T2DM) and metabolic syndrome. Objectives This study aimed to assess whether serum resistin is associated with insulin resistance and glucose concentration in males with T2DM. Patients and Methods Thirty two adult non-trained males with type II diabetes, 34-48 years old and 88-110 kg of body weight, participated in this study by accessible sampling. Fasting blood samples were collected from all participants in order to measure serum resistin, insulin and glucose concentration. Homeostasis Model Assessment of Insulin Resistance (HOMA-IR) was calculated using fasting insulin and glucose. Relations between variables were determined by Pearson correlations. |
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| کلیدواژه‌های انگلیسی مقاله |
Resistin,Body Weight,Insulin Resistance,Obesity |
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| نویسندگان مقاله |
یحیی سخنگو یی | yahya sokhanguei
department of physical education and sport sciences, islamshahr branch, islamic azad university, islamshahr, ir iran
سازمان اصلی تایید شده: دانشگاه آزاد اسلامی علوم و تحقیقات (Islamic azad university science and research branch)
مجتبی ایزدی | mojtaba eizadi
department of physical education and sport sciences, saveh branch, islamic azad university, saveh, ir iran; department of physical education and sport sciences, saveh branch, islamic azad university, saveh, ir iran. tel 98-2144549621
سازمان اصلی تایید شده: دانشگاه آزاد اسلامی علوم و تحقیقات (Islamic azad university science and research branch)
محمد تقی گودرزی | mohamad taghi goodarzi
research center for molecular medicine, hamadan university of medical sciences, hamadan iran
سازمان اصلی تایید شده: دانشگاه علوم پزشکی همدان (Hamadan university of medical sciences)
داود خورشیدی | davood khorshidi
department of physical education and sport sciences, saveh branch, islamic azad university, saveh, ir iran
سازمان اصلی تایید شده: دانشگاه آزاد اسلامی علوم و تحقیقات (Islamic azad university science and research branch)
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| نشانی اینترنتی |
http://www.avicennajb.com/index.php?page=article&article_id=26467 |
| فایل مقاله |
فایلی برای مقاله ذخیره نشده است |
| کد مقاله (doi) |
10.17795/ajmb-26467 |
| زبان مقاله منتشر شده |
fa |
| موضوعات مقاله منتشر شده |
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| نوع مقاله منتشر شده |
research-article |
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