|
|
Avicenna Journal of Medical Biochemistry، جلد ۱، شماره ۱، صفحات ۱۴-۲۲
|
|
|
| عنوان فارسی |
Comparison of the effects of clarified yogurt butter and commercial di-etary oils on serum fatty acid composition in rat |
|
| چکیده فارسی مقاله |
Objectives The link between dietary fat and heart disease has been established for decades. Although, the atherogenic effect of saturated fatty acids is somehow controversial, the cardioprotective effects of polyunsaturated fatty acids (PUFA) are clearly documented. This study investigated the effects of different dietary oils on serum fatty acid composition in rat. Methods Six week male Wistar rats (n=40) were randomly assigned into 5 groups and received chow diet for 3 weeks, before blood sample collection from 4 rats of each group. Remaining rats were then received chow diet or chow diet supplemented with yogurt butter, olive oil, soybean oil, or flaxseed oil providing 53% of energy from fat for another 4 weeks. Blood samples were then collected and serum fatty acid composition analysed by gas chromatography. Results Total saturated, monounsaturated, and n 6 and n 3 PUFA were significantly higher in rats received yogurt butter, olive oil, soybean oil, and flaxseed oil supplemented diets, respectively, compare to the controls (P< 0.05). In addition, the ratio of n 6:n 3 PUFA markedly decreased by consumption of flaxseed oil compare to other diets (P< 0.05). Rats received olive, soybean, and flaxseed oils showed significantly lower serum triacylglycerol compare to the control (P< 0.05). Moreover, no significant effect observed on serum cholesterol in rats consumed yogurt butter. Conclusion We clearly showed that the composition of dietary fat impact on serum fatty acid composition and consumption of yogurt butter had no significant atherogenic effects on serum total and LDL cholesterol. |
|
| کلیدواژه‌های فارسی مقاله |
|
|
| عنوان انگلیسی |
Comparison of the effects of clarified yogurt butter and commercial di-etary oils on serum fatty acid composition in rat |
|
| چکیده انگلیسی مقاله |
Objectives The link between dietary fat and heart disease has been established for decades. Although, the atherogenic effect of saturated fatty acids is somehow controversial, the cardioprotective effects of polyunsaturated fatty acids (PUFA) are clearly documented. This study investigated the effects of different dietary oils on serum fatty acid composition in rat. Methods Six week male Wistar rats (n=40) were randomly assigned into 5 groups and received chow diet for 3 weeks, before blood sample collection from 4 rats of each group. Remaining rats were then received chow diet or chow diet supplemented with yogurt butter, olive oil, soybean oil, or flaxseed oil providing 53% of energy from fat for another 4 weeks. Blood samples were then collected and serum fatty acid composition analysed by gas chromatography. Results Total saturated, monounsaturated, and n 6 and n 3 PUFA were significantly higher in rats received yogurt butter, olive oil, soybean oil, and flaxseed oil supplemented diets, respectively, compare to the controls (P< 0.05). In addition, the ratio of n 6:n 3 PUFA markedly decreased by consumption of flaxseed oil compare to other diets (P< 0.05). Rats received olive, soybean, and flaxseed oils showed significantly lower serum triacylglycerol compare to the control (P< 0.05). Moreover, no significant effect observed on serum cholesterol in rats consumed yogurt butter. Conclusion We clearly showed that the composition of dietary fat impact on serum fatty acid composition and consumption of yogurt butter had no significant atherogenic effects on serum total and LDL cholesterol. |
|
| کلیدواژه‌های انگلیسی مقاله |
|
|
| نویسندگان مقاله |
عسگر برخورداری | asgar barkhordari
department of pharmaceutical biotechnology, faculty of pharmacy, isfahan university of medical sciences
سازمان اصلی تایید شده: دانشگاه علوم پزشکی اصفهان (Isfahan university of medical sciences)
حیدر طویلانی | heidar tavilani
urology amp;amp; nephrology research center, hamadan university of medical sciences, hamadan iran
سازمان اصلی تایید شده: دانشگاه علوم پزشکی همدان (Hamadan university of medical sciences)
محمد عبدی | mohammad abdi
department of pathology and medical laboratory sciences, faculty of para medicine, kurdistan university of medical sci-ences, sanandaj, iran
جواد رنجبران | javad ranjbaran
department of biochemistry and nutrition, hamadan university of medical sciences, hamadan, iran
سازمان اصلی تایید شده: دانشگاه علوم پزشکی همدان (Hamadan university of medical sciences)
مهشید صالح آبادی | mahshid salehabadi
department of biochemistry and nutrition, hamadan university of medical sciences, hamadan, iran
سازمان اصلی تایید شده: دانشگاه علوم پزشکی همدان (Hamadan university of medical sciences)
ایرج خدادادی | iraj khodadadi
department of biochemistry and nutrition, hamadan university of medical sciences, hamadan, iran; department of biochemistry and nutrition, hamadan university of medical sciences, hamadan, iran , 98 8118380572
سازمان اصلی تایید شده: دانشگاه علوم پزشکی همدان (Hamadan university of medical sciences)
|
|
| نشانی اینترنتی |
http://www.avicennajb.com/index.php?page=article&article_id=19872 |
| فایل مقاله |
فایلی برای مقاله ذخیره نشده است |
| کد مقاله (doi) |
|
| زبان مقاله منتشر شده |
fa |
| موضوعات مقاله منتشر شده |
|
| نوع مقاله منتشر شده |
research-article |
|
|
|
برگشت به:
صفحه اول پایگاه |
نسخه مرتبط |
نشریه مرتبط |
فهرست نشریات
|