Avicenna Journal of Clinical Microbiology and Infection، جلد 1، شماره 3، صفحات 0-0
عنوان فارسی The Association Between Chlamydia pneumoniae Infection and Ischemic Stroke
چکیده فارسی مقاله Background Chlamydia pneumoniae has been linked with increased risk of cardiovascular diseases; however, data on stroke and cerebrovascular accidents are sparse. Objectives The aim of this study was to determine the association between C. pneumoniae infection and ischemic stroke. Patients and Methods In a case-control study, 141 patients, admitted with ischemic stroke, were compared with gender and age-matched control subjects (n = 141). Using an enzyme-linked immunosorbent assay kit, the presence of C. pneumoniae IgG and IgA in the patients’ sera was determined. The data were analyzed by SPSS software (version 15) and were compared between the two groups using T-test and chi square test. Results The mean ages of the case and control groups were 68.97 ± 12.29 and 66.95 ± 6.68 years old, respectively. The difference between these two groups was not statistically significant (P = 0.102). The seroprevalence of C. pneumoniae-specific IgG were 78.7% in the patients with stroke and 52.5% in the control group. The difference between the two groups was statistically significant (P = 0.0001). The seroprevalence of C. pneumoniae-specific IgA were 41.1% in the stroke and 15.6% in the control group. The difference between the two groups was statistically significant (P = 0.0001). Conclusions The results supported the hypothesis that serological evidence of C. pneumoniae infection may be associated with an increased risk of ischemic stroke and cerebrovascular accident.
کلیدواژه‌های فارسی مقاله Chlamydia pneumoniae،Cerebrovascular Accident،Stroke
عنوان انگلیسی The Association Between Chlamydia pneumoniae Infection and Ischemic Stroke
چکیده انگلیسی مقاله Background Chlamydia pneumoniae has been linked with increased risk of cardiovascular diseases; however, data on stroke and cerebrovascular accidents are sparse. Objectives The aim of this study was to determine the association between C. pneumoniae infection and ischemic stroke. Patients and Methods In a case-control study, 141 patients, admitted with ischemic stroke, were compared with gender and age-matched control subjects (n = 141). Using an enzyme-linked immunosorbent assay kit, the presence of C. pneumoniae IgG and IgA in the patients’ sera was determined. The data were analyzed by SPSS software (version 15) and were compared between the two groups using T-test and chi square test. Results The mean ages of the case and control groups were 68.97 ± 12.29 and 66.95 ± 6.68 years old, respectively. The difference between these two groups was not statistically significant (P = 0.102). The seroprevalence of C. pneumoniae-specific IgG were 78.7% in the patients with stroke and 52.5% in the control group. The difference between the two groups was statistically significant (P = 0.0001). The seroprevalence of C. pneumoniae-specific IgA were 41.1% in the stroke and 15.6% in the control group. The difference between the two groups was statistically significant (P = 0.0001). Conclusions The results supported the hypothesis that serological evidence of C. pneumoniae infection may be associated with an increased risk of ischemic stroke and cerebrovascular accident.
کلیدواژه‌های انگلیسی مقاله Chlamydia pneumoniae,Cerebrovascular Accident,Stroke
نویسندگان مقاله peyman eini - department of infectious diseases, brucellosis research center, hamadan university of medical sciences, hamadan, ir iran

fariba keramat - department of infectious diseases, brucellosis research center, hamadan university of medical sciences, hamadan, ir iran; department of infectious diseases, brucellosis research center, hamadan university of medical sciences, p. o. box 65168, hamadan, ir iran. tel 98-9181113281, fax 98-8138269808

nasim farajpoor - school of medicine, hamadan university of medical sciences, hamadan, ir iran

نشانی اینترنتی http://www.ajcmicrob.com/index.php?page=article&article_id=22165
فایل مقاله اشکال در دسترسی به فایل - ./files/site1/rds_journals/1795/article-1795-276839.pdf
کد مقاله (doi) 10.17795/ajcmi-22165
زبان مقاله منتشر شده fa
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نوع مقاله منتشر شده research-article
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