Avicenna Journal of Clinical Microbiology and Infection، جلد 3، شماره 4، صفحات 0-0
عنوان فارسی Occult Hepatitis B in Patients Co-Infected With Hepatitis C and Human Immunodeficiency Viruses
چکیده فارسی مقاله Conclusions The significant number of coinfected HIV-HCV patients only had HBcAb positive test without detectable HBV-DNA. Further studies for detection of HBV-DNA in both serum and liver biopsy specimens may help clarify the impact of HBV infection in coinfected HIV/HCV patients. Results Of 103 HIV-HCV coinfected patients, both HBsAg and HBcAb were positive in 7 patients (6.8%), negative in 44 (42.7%) patients and 52 (50.5%) of all patients were HBsAg negative and HBcAb positive, which positivity of HBsAg had statistical correlation with positivity of HBcAb. In the last group HBsAb and HBV-DNA PCR were done, which resulted in the titer of antibody to be positive in 4 patients (7.7%) and the PCR to be negative in all (100%) patients. Objectives Diagnosis of the occult hepatitis B virus (HBV) infection in patients co-infected with human immunodeficiency virus (HIV) and hepatitis C virus (HCV) is important due to the fact that the HBV infection may have a clinical impact on liver disease in coinfected HIV/HCV patients. Isolated hepatitis B core antibody (HBcAb) positive HBV infection has been reported in HIV patients. The aim of this study was to determine the occult hepatitis B in patients co-infected with HCV-HIV. Methods In a cross-sectional study, hepatitis B surface antigen (HBsAg) and HBcAb tests were performed for all HIV-HCV co-infected patients, referred to the HIV Clinic of Hamadan. HBsAb was requested for HBsAg negative-HBcAb positive individuals and in the case of negative HBsAb, HBV-DNA PCR was performed. Finally the collected data was analyzed with SPSS.
کلیدواژه‌های فارسی مقاله HIV،Hepatitis B،Hepatitis C،Diagnosis
عنوان انگلیسی Occult Hepatitis B in Patients Co-Infected With Hepatitis C and Human Immunodeficiency Viruses
چکیده انگلیسی مقاله Conclusions The significant number of coinfected HIV-HCV patients only had HBcAb positive test without detectable HBV-DNA. Further studies for detection of HBV-DNA in both serum and liver biopsy specimens may help clarify the impact of HBV infection in coinfected HIV/HCV patients. Results Of 103 HIV-HCV coinfected patients, both HBsAg and HBcAb were positive in 7 patients (6.8%), negative in 44 (42.7%) patients and 52 (50.5%) of all patients were HBsAg negative and HBcAb positive, which positivity of HBsAg had statistical correlation with positivity of HBcAb. In the last group HBsAb and HBV-DNA PCR were done, which resulted in the titer of antibody to be positive in 4 patients (7.7%) and the PCR to be negative in all (100%) patients. Objectives Diagnosis of the occult hepatitis B virus (HBV) infection in patients co-infected with human immunodeficiency virus (HIV) and hepatitis C virus (HCV) is important due to the fact that the HBV infection may have a clinical impact on liver disease in coinfected HIV/HCV patients. Isolated hepatitis B core antibody (HBcAb) positive HBV infection has been reported in HIV patients. The aim of this study was to determine the occult hepatitis B in patients co-infected with HCV-HIV. Methods In a cross-sectional study, hepatitis B surface antigen (HBsAg) and HBcAb tests were performed for all HIV-HCV co-infected patients, referred to the HIV Clinic of Hamadan. HBsAb was requested for HBsAg negative-HBcAb positive individuals and in the case of negative HBsAb, HBV-DNA PCR was performed. Finally the collected data was analyzed with SPSS.
کلیدواژه‌های انگلیسی مقاله HIV,Hepatitis B,Hepatitis C,Diagnosis
نویسندگان مقاله mohammad mahdi majzoobi - brucellosis research center, hamadan university of medical sciences, hamadan, iran

seyyed hamid hashemi - brucellosis research center, hamadan university of medical sciences, hamadan, iran; brucellosis research center, hamadan university of medical sciences, hamadan, iran. tel 98-8138272154, fax 98-8138272154

hosein mahjoob - department of epidemiology and statistics, hamadan university of medical sciences, hamadan, iran

saeid khakizadeh - department of pathology, hamadan university of medical sciences, hamadan, iran

mina nikbakht - consult center for hiv, hamadan university of medical sciences, hamadan, iran

نشانی اینترنتی http://www.ajcmicrob.com/index.php?page=article&article_id=35247
فایل مقاله اشکال در دسترسی به فایل - ./files/site1/rds_journals/1795/article-1795-276866.pdf
کد مقاله (doi) 10.17795/ajcmi-35247
زبان مقاله منتشر شده fa
موضوعات مقاله منتشر شده
نوع مقاله منتشر شده research-article
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