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Avicenna Journal of Clinical Microbiology and Infection، جلد ۲، شماره ۱، صفحات ۰-۰
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| عنوان فارسی |
Association Between Epstein-Barr Virus Infection and B-Cell Lymphoproliferative Diseases: A Case-Control Study |
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| چکیده فارسی مقاله |
Results Of the 89 subjects, 53 were male and 36 females, aged 14 to 82 years. There was no significant difference between EBV seroprevalence in the patients with lymphoma and multiple myeloma, and the healthy subjects. Conclusions The results of the current study indicated no relationship between latent EBV infection and lymphoma or multiple myeloma. However, further studies with larger sample sizes are required. Patients and Methods In the current case-control study, a total of 43 patients with lymphoma and multiple myeloma and 46 age/sex-matched healthy people were included. After taking written consent, serum samples were taken from all subjects. The level of IgG against viral capsid antigen was measured using ELISA. Antibody titers > 5 U/mL was considered as positive. Data were analyzed using Stata 11 software. Objectives The current study aimed to evaluate the relationship between EBV infection and B-cell lymphoproliferative disorders, including lymphoma and multiple myeloma. Background Epstein-Barr Virus (EBV) is a member of the Herpesviridae family that has infected more than 90% of the worlds’ population. EBV is now considered etiologically associated with the endemic Burkitt's lymphoma, Hodgkin disease, and nasopharyngeal carcinoma. Recent findings show the association between EBV infection and other malignancies. |
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| کلیدواژه‌های فارسی مقاله |
Patient،Lymphoma،Multiple Myeloma |
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| عنوان انگلیسی |
Association Between Epstein-Barr Virus Infection and B-Cell Lymphoproliferative Diseases: A Case-Control Study |
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| چکیده انگلیسی مقاله |
Results Of the 89 subjects, 53 were male and 36 females, aged 14 to 82 years. There was no significant difference between EBV seroprevalence in the patients with lymphoma and multiple myeloma, and the healthy subjects. Conclusions The results of the current study indicated no relationship between latent EBV infection and lymphoma or multiple myeloma. However, further studies with larger sample sizes are required. Patients and Methods In the current case-control study, a total of 43 patients with lymphoma and multiple myeloma and 46 age/sex-matched healthy people were included. After taking written consent, serum samples were taken from all subjects. The level of IgG against viral capsid antigen was measured using ELISA. Antibody titers > 5 U/mL was considered as positive. Data were analyzed using Stata 11 software. Objectives The current study aimed to evaluate the relationship between EBV infection and B-cell lymphoproliferative disorders, including lymphoma and multiple myeloma. Background Epstein-Barr Virus (EBV) is a member of the Herpesviridae family that has infected more than 90% of the worlds’ population. EBV is now considered etiologically associated with the endemic Burkitt's lymphoma, Hodgkin disease, and nasopharyngeal carcinoma. Recent findings show the association between EBV infection and other malignancies. |
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| کلیدواژه‌های انگلیسی مقاله |
Patient,Lymphoma,Multiple Myeloma |
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| نویسندگان مقاله |
سید حمید هاشمی | seyyed hamid hashemi
brucellosis research center, department of infectious diseases, hamadan university of medical sciences, hamadan, ir iran; brucellosis research center, department of infectious diseases, hamadan university of medical sciences, hamadan, ir iran. tel 98-8138274192, fax 98-8138276010
سازمان اصلی تایید شده: دانشگاه علوم پزشکی همدان (Hamadan university of medical sciences)
محمد عباسی | mohammad abbasi
department of oncology, hamadan university of medical sciences, hamadan, ir iran
سازمان اصلی تایید شده: دانشگاه علوم پزشکی همدان (Hamadan university of medical sciences)
مهرداد حاجیلویی | mehrdad hajilooi
department of immunology, hamadan university of medical sciences, hamadan, ir iran
سازمان اصلی تایید شده: دانشگاه علوم پزشکی همدان (Hamadan university of medical sciences)
جلال پورالعجل | jalal poorolajal
research center for health sciences, department of epidemiology and biostatics, school of public health, hamadan university of medical sciences, hamadan, ir iran
سازمان اصلی تایید شده: دانشگاه علوم پزشکی همدان (Hamadan university of medical sciences)
لیدا لک زاده | lida lakzadeh
brucellosis research center, department of infectious diseases, hamadan university of medical sciences, hamadan, ir iran
سازمان اصلی تایید شده: دانشگاه علوم پزشکی همدان (Hamadan university of medical sciences)
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| نشانی اینترنتی |
http://www.ajcmicrob.com/index.php?page=article&article_id=23059 |
| فایل مقاله |
اشکال در دسترسی به فایل - ./files/site1/rds_journals/1795/article-1795-276876.pdf |
| کد مقاله (doi) |
10.17795/ajcmi-23059 |
| زبان مقاله منتشر شده |
fa |
| موضوعات مقاله منتشر شده |
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| نوع مقاله منتشر شده |
research-article |
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