Avicenna Journal of Dental Research، جلد ۸، شماره ۴، صفحات ۰-۰

عنوان فارسی Comparison of Whole Salivary Lactate Dehydrogenase Level in Patients With and Without Periodontal Disease
چکیده فارسی مقاله Background Tracking various biomarkers in serum, gingival crevicular fluid (GCF), and saliva has been introduced as a diagnostic tool for periodontal disease detection. Objectives The aim of this study was to compare salivary lactate dehydrogenase (LDH) levels in subjects with periodontal disease and levels in subjects without periodontal disease. Conclusions Salivary LDH levels can be used as marker of periodontal disease for screening periodontitis in large populations. Results The mean LDH levels in the test and control groups were 1071.67 ± 731.004 and 550.91 ± 217.215, respectively. As the level of statistical significance was set at P < 0.05, data analysis showed a significant difference between the LDH enzymatic level in the test and control groups (P = 0.000). Comparison of the LDH enzymatic level in subjects with different genders in the test and control groups showed no significant differences (P = 0.340). Materials and Methods In this case-control study, 170 patients at Hamadan faculty of Dentistry, including patients with periodontal disease and patients with normal periodontium, were selected and divided into test and control groups. Unstimulated saliva was collected in the same situation from the test and control groups. Each saliva sample was analyzed to measure salivary LDH level on the day of collection, by using commercially available kits according to the manufacturers’ instructions. A statistical T-test was employed to evaluate significant differences among groups.
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عنوان انگلیسی Comparison of Whole Salivary Lactate Dehydrogenase Level in Patients With and Without Periodontal Disease
چکیده انگلیسی مقاله Background Tracking various biomarkers in serum, gingival crevicular fluid (GCF), and saliva has been introduced as a diagnostic tool for periodontal disease detection. Objectives The aim of this study was to compare salivary lactate dehydrogenase (LDH) levels in subjects with periodontal disease and levels in subjects without periodontal disease. Conclusions Salivary LDH levels can be used as marker of periodontal disease for screening periodontitis in large populations. Results The mean LDH levels in the test and control groups were 1071.67 ± 731.004 and 550.91 ± 217.215, respectively. As the level of statistical significance was set at P < 0.05, data analysis showed a significant difference between the LDH enzymatic level in the test and control groups (P = 0.000). Comparison of the LDH enzymatic level in subjects with different genders in the test and control groups showed no significant differences (P = 0.340). Materials and Methods In this case-control study, 170 patients at Hamadan faculty of Dentistry, including patients with periodontal disease and patients with normal periodontium, were selected and divided into test and control groups. Unstimulated saliva was collected in the same situation from the test and control groups. Each saliva sample was analyzed to measure salivary LDH level on the day of collection, by using commercially available kits according to the manufacturers’ instructions. A statistical T-test was employed to evaluate significant differences among groups.
کلیدواژه‌های انگلیسی مقاله

نویسندگان مقاله ژانت مرادی حقگو | janet moradi haghgoo
department of periodontology, dental faculty, hamadan university of medical sciences, hamadan, ir iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی همدان (Hamadan university of medical sciences)

سارا سهیلی فر | sara soheilifar
department of periodontology, dental faculty, hamadan university of medical sciences, hamadan, ir iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی همدان (Hamadan university of medical sciences)

محسن بیدگلی | mohsen bidgoli
department of periodontology, dental faculty, hamadan university of medical sciences, hamadan, ir iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی همدان (Hamadan university of medical sciences)

ندا rastegarfard | neda rastegarfard
department of periodontology, dental faculty, hamadan university of medical sciences, hamadan, ir iran; department of periodontics, dental faculty, hamadan university of medical sciences, hamadan, ir iran. tel 98-8138381085, fax 98-8138381085

سازمان اصلی تایید شده: دانشگاه علوم پزشکی همدان (Hamadan university of medical sciences)

مارال صارمی | maral saremi
dental faculty, hamadan university of medical sciences, hamadan, ir iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی همدان (Hamadan university of medical sciences)

ثمره کفیل زاده | samare kafilzade
department of periodontology, dental faculty, hamadan university of medical sciences, hamadan, ir iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی همدان (Hamadan university of medical sciences)


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کد مقاله (doi) 10.17795/ajdr-29026
زبان مقاله منتشر شده fa
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